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Helping p53 Out

Scientists publishing in the journal Clinical Cancer Research this week have found a possible role for miR-192 in the p53 tumor suppressor network. By increasing expression of miR-192 in colon cancer cells, they were able to trigger both G1 and G2 cell cycle arrest, but only in cells with wild-type p53. They found that p53 and p21, both tumor suppressor genes, were overexpressed in cells that also overexpressed miR-192.

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The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.

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