Helping p53 Out

Scientists publishing in the journal Clinical Cancer Research this week have found a possible role for miR-192 in the p53 tumor suppressor network. By increasing expression of miR-192 in colon cancer cells, they were able to trigger both G1 and G2 cell cycle arrest, but only in cells with wild-type p53. They found that p53 and p21, both tumor suppressor genes, were overexpressed in cells that also overexpressed miR-192.

To read the full story....

Register for Free.

Already have a GenomeWeb or 360Dx account?
Login Now.

In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.