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Helping p53 Out

Scientists publishing in the journal Clinical Cancer Research this week have found a possible role for miR-192 in the p53 tumor suppressor network. By increasing expression of miR-192 in colon cancer cells, they were able to trigger both G1 and G2 cell cycle arrest, but only in cells with wild-type p53. They found that p53 and p21, both tumor suppressor genes, were overexpressed in cells that also overexpressed miR-192.

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Matt Hancock, the UK health secretary, is calling for the swift rollout of predictive genetic tests, the Guardian reports.

A WHO panel is calling for a global registry of human germline gene-editing projects, according to Stat News.

Vox writes that lab mishaps involving pathogens are quite common.

In Genome Biology this week: analysis of wild and cultivated peach genomes, Hi-C-based pipeline for assembling microbial genomes from metagenomic data, and more.