Helping p53 Out

Scientists publishing in the journal Clinical Cancer Research this week have found a possible role for miR-192 in the p53 tumor suppressor network. By increasing expression of miR-192 in colon cancer cells, they were able to trigger both G1 and G2 cell cycle arrest, but only in cells with wild-type p53. They found that p53 and p21, both tumor suppressor genes, were overexpressed in cells that also overexpressed miR-192.

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The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.