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Heart Healthy, or Healthy Heart? Learning From Nutrigenomics

In an interview posted to MIT’s Technology Review online magazine, Jose Ordovas, director of the Nutrition and Genomics Laboratory at Tufts University, talks about recent nutrigenomic work. After taking a look at data from the ongoing Framingham Heart Study, Ordovas found that certain genetic variants, including variations in a gene known as apoliprotein E (ApoE), can be risk factors for heart disease.

If you knew how your genes might betray you, would you love them differently? Read the entire interview to find out what this nutrigenomics leader has to say.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.