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Hard Choices

For his book Am I My Genes? Confronting Fate and Family Secrets in an Age of Genetic Testing, Robert Klitzman, a clinical psychiatrist at Columbia University, interviewed a number of people with breast cancer, Huntington's disease, or alpha-1 antitrypsin deficiency. Based on knowing their genetics, these individuals "had to make very difficult decisions — whom to tell, and whether to have children, abort fetuses, screen embryos, or adopt," Klitzman tells Bloomberg News' Manuela Hoelterhoff. Hoelterhoff says that "confusion, anger, and regret infuse [the patients'] stories as they unfold."

Klitzman, himself, has not had his genes scanned. "I guess I like my life the way it is. I don't want to complicate it," he says.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.