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Happy Darwin Day!: Feb 12, 2010

darwinToday is Charles Darwin's 201st birthday and there are many events around the world in celebration. Kevin Zelnio will be giving a talk about Darwin and his contributions to marine science at Duke University's Marine Lab in Beaufort, NC and in Dublin, Ireland the annual Darwin Day Lecture is entitled "Noah's Ark or Noah's Coffin - The challenge for biodiversity" and will be given by Nigel Monaghan from the National Museum of Ireland.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.