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Hamlet's Other Question

At her blog, Dr. Shellie wonders whether she should go through long derivations while teaching a graduate-level class this semester. She has been trying to find a balance between emphasizing concepts and rigorous derivations, especially as students tend to get lost following all the algebra. "I am also trying to encourage student thinking and participation during class. This tends to tilt things toward the hand-wavy side, as more student participation = fewer lines of algebra on the chalkboard," she adds.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.