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A GWAS for Gout

Researchers led by Caroline Fox report in The Lancet that they've found three genes associated with gout. In genome-wide association studies of 7,699 Framingham study participants and 4,148 Rotterdam cohort study participants, the researchers looked for genes associated with serum uric acid. The SNPs identified from that study were then confirmed in both black and white Atherosclerosis Risk in Communities participants. Having all three gene variants -- SCLA29, ABCG2, and SLC17A3, which are thought to be involved in urate transport -- can increase the risk for gout by 40-fold, says a Health Day story. Fox tells them that these genes "can potentially be used as novel drug targets."

The Scan

Could Cost Billions

NBC News reports that the new Alzheimer's disease drug from Biogen could cost Medicare in the US billions of dollars.

Not Quite Sent

The Biden Administration likely won't meet its goal of sending 80 million SARS-CoV-2 vaccine doses abroad by the end of the month, according to the Washington Post.

DTC Regulation Proposals

A new report calls on UK policymakers to review direct-to-consumer genetic testing regulations, the Independent reports.

PNAS Papers on Mosquito MicroRNAs, Acute Kidney Injury, Trichothiodystrophy

In PNAS this week: microRNAs involved in Aedes aegypti reproduction, proximal tubule cell response to kidney injury, and more.