A GWAS Cheat Sheet

At Genomes Unzipped, Jeff Barrett gives a how-to on determining whether a genome-wide association study is "a landmark finding or a dud." Five factors to take into consideration, he says, are sample size, quality control, confounders, replication, and biology. "The biggest challenge to successfully carrying out a GWAS is getting good, clean genotype data. Pay close attention not only to the standard QC metrics ...

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