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GWAS and Differences in DNA Between Tissues

A study from McGill University's Morris Schweitzer found that three SNPs found in diseased tissue from abdominal aortic aneurysm patients were not present in blood samples from the same patients, reports The Scientist. Schweitzer's group also tested aortic and blood samples from healthy people and saw the same inconsistency. Because of these differences, genome-wide association studies may be missing out by focusing on what's in blood samples. "I think they may not be accurate because they might not reflect what's in the tissue," Schweitzer says.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.