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Gut Typing

A team of researchers led by the European Molecular Biology Laboratory's Peer Bork reports that there are three human gut microbiome enterotypes in Nature this week. Using 22 newly sequenced fecal metagenomes from people from four countries as well as previously published data, the researchers identified three clusters that people's gut microbiomes fall into and found that those clusters are not specific to nations or continents. The enterotypes do differ in composition and enzyme production — enterotype 1, which is marked by high levels of Bacteroides, produces more vitamin B7 enzymes, while Enterotype 2, which has many bacteria from the genus Prevotella, makes more thiamine enzymes, writes Carl Zimmer in The New York Times. "It's an important advance," the University of Colorado's Rob Knight, who was not involved in the research, told the Times. "It's the first indication that human gut ecosystems may fall into distinct types," Knight added. Bork told the Times that as more research and more samples are needed for further investigations into these enterotypes, his group has expanded its study to include 400 people.

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.