To uncover genes associated with aging, researchers led by Simon Melov gathered whole-genome expression profiles from 104 C. elegans specimens over the course of their lives. The individual worms were then scored for age-related phenotypes to determine which transcriptional profiles are associated with physiological or chronological age. "This is the first evidence that physiological age can be predicted non-subjectively. This is a first step; our results were not perfect, but we were able to predict the ages of the animals 70 percent of the time, which is far better than anything that has been done before," says Melov in this HealthDay story. The results were reported in Aging Cell.
Guess This Means We'll Have to Stop Lying About Our Age
Nov 20, 2008