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Got Short Reads?

The Short Read Archive at the National Center for Biotechnology Information is up and running, reports the current issue of NCBI News. Head to the archive to sift through, add to, or download sequencing data from next-generation platforms including 454, Complete Genomics, HeliScope, Illumina, and SOLiD. In addition to the browser interface and Entrez database, the SRA also offers a Blast search of the reads. "The power and capabilities of the SRA site will expand to provide better and more powerful options for searching and connecting these data to other resources," NCBI News says.

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.