Goodbye, Mr. Wizard

The TV star who turned generations of kids, from baby boomers to their children, onto science died on Tuesday. Don Herbert, better known as Mr. Wizard, died of bone cancer at age 89. His show illustrated how things found around the house could be used in experiments and he encouraged kids to try science out at home.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.