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A Good Day for Clouds

It looks like cloud computing has hit the mainstream: has a Q&A with Paul Maritz, CEO of virtual machine software vendor VMware. In the interview, he touts the glories of cloud computing, the latest HPC trend that lets users operate virtual compute nodes and store data through pay-per-use service plans offered by Google, IBM, Amazon, and others. And even though a large portion of VMware's business strategy rests on the hope that cloud computing really does take off, Maritz manages to quell the hype and outline some of the real challenges when it comes to implementation. "How do you operate at this scale, how do you make things essentially bulletproof in terms of reliability, security and privacy. Those are tough things to do...Companies have to learn that as they go forward. This is why this world isn't going to leap up into the cloud tomorrow," he says.


The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.