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A Good Choice of Pet

High-throughput analysis of proteins in naked mole rats shows that they live longer because their proteins are more resistant to unfolding, says an article in Technology Review. The work, published in PNAS this week, looked across oxidation states of protein cysteines to find how the longest-lived rodent can withstand oxidative stress, which is thought to be a culprit in aging. When compared to mice, mole rates had less age-related oxidation damage to thiol groups and age-associated up-regulation of homeostatic proteolytic activity. "Our first plan is to try and identify the proteins that protect and are protected in naked mole rats," coauthor Rochelle Buffenstein says.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.