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Gobble Gobble, Cluck Cluck

Pass the squash, pass the stuffing, pass the Meleagris gallopavo? Just in time for Thanksgiving in the US, researchers in the Netherlands report their discovery of two inter- and 57 intra-chromosomal rearrangements between the turkey and chicken genomes. In genotyping more than 1,000 birds for 775 SNPs, the team constructed a linkage map of 531 markers in 28 groups, the largest of which contains 81 loci. In a BMC Genomics paper, the team shows that the M. gallopavo and chicken genomes are both "highly conserved." While this probably won't influence your holiday menu-planning, Daily Scan says it could make for an interesting dinnertime conversation.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.