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Getting Them to Stick

Derek Lowe tosses around some ideas for using small molecules as binding partners for immobilizing proteins to solid supports like beads and chips. Affinity chromatography is one way; surface plasmon resonance, which can tell with great sensitivity if something is sticking close to a solid surface, is another current approach that's making headway.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.