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Getting Them to Stick

Derek Lowe tosses around some ideas for using small molecules as binding partners for immobilizing proteins to solid supports like beads and chips. Affinity chromatography is one way; surface plasmon resonance, which can tell with great sensitivity if something is sticking close to a solid surface, is another current approach that's making headway.

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An analysis of blood donations suggests SARS-CoV-2 was present in the US weeks earlier than thought, according to NPR.

The Guardian reports that DeepMind Technologies' AlphaFold can predict how proteins fold.

CNBC reports that a US Centers for Disease Control and Prevention advisory panel is to vote on how to distribute COVID-19 vaccines.

In PNAS this week: targeting progesterone signaling in ovarian cancer, LINE-1 retrotransposition events in adenocarcinomas, and more.