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Getting Personal: Feb 10, 2009

As our Daily News team reports, the US Food and Drug Administration is creating a new position to focus on genomics-related programs. Liz Mansfield, who has worked on science policy in the past, will fill the new post. Over at Science Progress, Michael Rugnetta says, "The position is significant because it heralds the FDA's focus on developing approaches to personalized medicine." However, Rugnetta later adds that the US healthcare system is a long ways away from incorporating personalized medicine into everyday clinical care. Two initiatives that he says are needed to see that day are the "adoption of digital health records and a reformed reimbursement process that rewards positive clinical outcomes instead of just additional procedures and tests."

Filed under

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.