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Getting It to Work for You

Keith Robison's interest in next-gen sequencing is "shifting from hobby to work-central" and so in a recent blog post he discusses a new Nature Methods paper describing a program that helps identify indels. The program, called MoDIL, exhibited greater than 95 percent sensitivity in detecting indels of 20 base pairs or larger. "The program also explicitly models heterozygosity, allowing it to find heterozygous indels," Robison adds.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.