Keith Robison's interest in next-gen sequencing is "shifting from hobby to work-central" and so in a recent blog post he discusses a new Nature Methods paper describing a program that helps identify indels. The program, called MoDIL, exhibited greater than 95 percent sensitivity in detecting indels of 20 base pairs or larger. "The program also explicitly models heterozygosity, allowing it to find heterozygous indels," Robison adds.
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