Skip to main content
Premium Trial:

Request an Annual Quote

Getting Bacteria to Eat More

Tech Review spotlights work in Anthony Sinskey's lab on Rhodococcus opacus, a soil microbe that can eat sugars and toxins, related to biofuels. Sinskey and his colleagues have sequenced the bacteria's genome and mapped its genes to its metabolic pathways in hopes that they can learn how it is so efficient at producing tryacylglycerols, which can be converted to biodiesel. They have also engineered a Rhodococcus strain so it can feed on glucose and xylose, and another that eats a biodiesel production byproduct, glycerol. "I don't think I'm far behind lots of companies that have lots of publicity in this area," Sinskey says. "I think in two to three years I will have a robust process."

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.