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Get into the Sciences

Europe may soon be facing a shortage of scientists, reports Scientific Blogging. As not enough young people are going into the sciences or mathematics, a group of European education ministries, large companies, and the European Commission have begun a program called InGenious that aims to show young people that having scientific skills can help them get a job, to encourage women and minorities to study science, and to show how science can affect people's lives. "The new group worries this training gap is threatening the future of Europe's economic recovery due to the lack of qualified scientific and technical human resources, the key drivers of scientific progress and innovation," Scientific Blogging says.

The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.