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Genomics in Africa

Charles Rotimi, director of National Institutes of Health's Center for Research on Genomics and Global Health, believes that all human populations must be included in genomic research for genomics to have an impact on societal problems like hunger and disease, according to The Lancet's Kelly Morris. Rotimi recently launched the Human Heredity and Health in Africa project to conduct population-based studies there. "Rotimi is concerned to involve Africans in genetic epidemiology, both as participants and researchers," Morris says. "A comprehensive understanding of population and ethnic differences requires a robust appreciation of human history." Rotimi hopes the project will lead to increased collaborations among African researchers, and an increased ability for those investigators to compete for international funding.

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.