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Genetic Link to 'The King’s Speech'?

Suzanna Elvidge at Genome Engineering asks whether King George VI's "struggle with stammering," as chronicled in the Academy Award-winning film "The King's Speech," had a genetic basis. In reflecting on research presented by Dennis Drayna and his colleagues at the National Institutes of Health during AAAS 2011, in which the team "linked stammering with the GNPTAB, PNPTG, and NAGPA genes," Elvidge says that this work "will help to confirm stammering as a neurological rather than a behavioral disorder." She adds that "therapeutics that correct the folding of the mutated proteins may have potential in the treatment of stammering, and knowledge of the mutations could lead to the development of diagnostics that help identify stammering that is likely to continue beyond childhood."

The Scan

Boosters Chasing Variants

The New York Times reports that an FDA advisory panel is to weigh updated booster vaccines for COVID-19.

Not Yet

The World Health Organization says monkeypox is not yet a global emergency, the Washington Post reports.

More Proposed for Federal Research

Science reports that US House of Representatives panels are seeking to increase federal research funding.

PLOS Papers on Breast Cancer Metastasis, Left-Sided Cardiac Defects, SARS-CoV-2 Monitoring

In PLOS this week: link between breast cancer metastasis and CLIC4, sequencing analysis of left-sided cardiac defects, and more.