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Genetic Diversity in South Asia? Not So Much

"Although India comprises more than one sixth of the world's human population, it has largely been omitted from genomic surveys that provide the backdrop for association studies of genetic disease." So begin Noah Rosenberg et al. in PLoS Genetics. They analyzed 1,200 genome-wide polymorphisms in 432 individuals from 15 Indian populations - all Indian-born but residing in the United States. They conclude: 

Populations from India, and groups from South Asia more generally, form a genetic cluster, so that individuals placed within this cluster are more genetically similar to each other than to individuals outside the cluster. However, the amount of genetic differentiation among Indian populations is relatively small. ...Genetic variation in India is distinctive with respect to the rest of the world, but...the level of genetic divergence is smaller in Indians than might be expected for such a geographically and linguistically diverse group.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.