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The Gene for Lymphatic Vessels

In early online publication in Nature, researchers show that the transcription factor Sox18 induces development of the lymphatic vasculature in mice. Australian and Italian scientists used a range of assays to show that Sox18 acts as a molecular switch and causes differentiation of lymphatic endothelial cells. The team will now focus on finding genes regulated by Sox18 and determining how this regulation occurs, reports this story in Medical News Today. "If we know how to prevent lymphatic vessels from forming, then we will be a lot closer to halting the spread of tumors through the body. Conversely, if we know how to stimulate the formation of these vessels, then it might be possible to treat diseases such as lymphedema," lead author Peter Koopman says.

The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.