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A Gene Behind Type I Diabetes

A group of researchers, led by Constantin Polychronakos, identified a type I diabetes gene through a two-stage genome-wide association study. They also report in the advance online section of Nature that they predict the gene product of KIAA0350 to be a lectin and they hypothesize that a change to its binding site on an activating cytotoxic T-cell could result in the autoimmune response seen in type I diabetes.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.