Skip to main content
Premium Trial:

Request an Annual Quote

Full Genome Sequences: It's Been a Good Run -- Is It Over?

Omics! Omics! offers a thoughtful post on the era of full genome sequencing. Blogger Keith Robison considers the decade-old field, noting some of its successes and excitement -- and taking a moment to lay out some of the missing pieces among sequenced organisms.

He also refers to a post at the Evolgen blog, which published the rumor that NHGRI will no longer be accepting white papers to sequence full genomes. While there's no definitive answer on the NHGRI's stance, the post did spark a lively conversation on the merit of finished genome sequences and the state of funding.

 

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.