A Frustration

Adaptive Complexity’s Michael White writes that the big questions in biology — such as what makes us human — are difficult to answer using molecular biology. He writes that scientists can associate genes with a process, but not at going from the molecular biology level back up to the organismal level. “In other words, we're good finding causal links between traits and genes. And thanks to genomics, we know the molecular function of many of those genes.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.