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NIH is coming off a budget binge: the money given to the agency from the 2009 American Recovery and Reinvestment Act is about to run out. Next month, the last of the money will be disbursed and the recipients are required to spend most of it by September 2011, says Nature's Meredith Wadman. Now, researchers are looking to Francis Collins to figure out a solution.

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The New York Times reports that experts pushed during a meeting of an FDA advisory board for the agency to require more safety data from SARS-CoV-2 vaccine trials.

The UK and the European Union have come to a sticking point in the negotiation of how the UK might remain involved in the Horizon Europe research program, the Guardian reports.

The Washington Post reports Moderna expects that it will have enough data on its candidate SARS-CoV-2 vaccine to submit to regulatory authorities by mid-November.

In Science this week: ANXA11 variants affect calcium homeostasis and stress granule disassembly in ALS, and more.