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Forever Young Means...You Can Publish More Papers

Reporting in Nature Medicine, researchers at Yeshiva University have used transgenic mice to turn on a process that helps keep the liver of older mice young and healthy. Using a double transgenic mouse model that could be modulated to selectively increase the number of receptors for damaged proteins, they found that the process of chaperone-mediated autophagy (CMA) could be controlled to allow mice to continuously degrade and recycle proteins that accumulate with old age. Functionally, this could have significance for diseases like Alzheimer's or Parkinson's, they say. "It's not often you see studies where they have managed to improve function in this way," says Thomas von Zglinicki, Professor of Cellular Gerontology at Newcastle University, in a BBC article.

The Scan

Could Cost Billions

NBC News reports that the new Alzheimer's disease drug from Biogen could cost Medicare in the US billions of dollars.

Not Quite Sent

The Biden Administration likely won't meet its goal of sending 80 million SARS-CoV-2 vaccine doses abroad by the end of the month, according to the Washington Post.

DTC Regulation Proposals

A new report calls on UK policymakers to review direct-to-consumer genetic testing regulations, the Independent reports.

PNAS Papers on Mosquito MicroRNAs, Acute Kidney Injury, Trichothiodystrophy

In PNAS this week: microRNAs involved in Aedes aegypti reproduction, proximal tubule cell response to kidney injury, and more.