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Forever Young Means...You Can Publish More Papers

Reporting in Nature Medicine, researchers at Yeshiva University have used transgenic mice to turn on a process that helps keep the liver of older mice young and healthy. Using a double transgenic mouse model that could be modulated to selectively increase the number of receptors for damaged proteins, they found that the process of chaperone-mediated autophagy (CMA) could be controlled to allow mice to continuously degrade and recycle proteins that accumulate with old age. Functionally, this could have significance for diseases like Alzheimer's or Parkinson's, they say. "It's not often you see studies where they have managed to improve function in this way," says Thomas von Zglinicki, Professor of Cellular Gerontology at Newcastle University, in a BBC article.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.