Fixed It

Researchers working with induced pluripotent stem cells have struggled with a few deficiencies that have made the cells less desirable than embryonic stem cells for the treatment of disease. For one thing, says, Popular Science's Rebecca Boyle, iPS cells contain the same mutations as the person they're taken from, and current gene editing techniques to correct these deficiencies have led to cancer in mice and other side effects.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.