First Things First

As the UK's National Health Service takes on a £100 million initiative to sequence about 100,000 people, it has a number of questions to answer and challenges to overcome, writes Caroline Wright at Genomes Unzipped. The most pressing one, she adds, "will be to implement genomic knowledge in the clinic."

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.