First Things First

As the UK's National Health Service takes on a £100 million initiative to sequence about 100,000 people, it has a number of questions to answer and challenges to overcome, writes Caroline Wright at Genomes Unzipped. The most pressing one, she adds, "will be to implement genomic knowledge in the clinic."

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The president of France's National Research Agency has resigned, according to Nature News.

A senator wants a "right-to-try" provision in the US Food and Drug Administration funding bill, but an ethicist says at Stat News that it would undermine the role of clinical trials.

In PNAS this week: red algae Porphyra umbicalis genome, deep neural network model for sequencing peptides, and more.

The Guardian's Barbara Ellen has tried out some DNA testing services to see whether they provide valuable information.