NIH and Notre Dame researchers have used gene expression analysis to look at changes associated with chloroquine resistance in Plasmodium falciparum, a parasite that causes malaria in humans. In this PLoS ONE study, they looked at three different clones that had unique mutations in the PfCRT gene, a gene that confers resistance to chloroquine, in parasites grown with and without chloroquine.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.