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Finding Out What Makes P. Falciparum Tick

NIH and Notre Dame researchers have used gene expression analysis to look at changes associated with chloroquine resistance in Plasmodium falciparum, a parasite that causes malaria in humans. In this PLoS ONE study, they looked at three different clones that had unique mutations in the PfCRT gene, a gene that confers resistance to chloroquine, in parasites grown with and without chloroquine. In the 35 genes where they found altered expression levels, most of the up-regulated genes were involved in invasion, cell growth and development, signal transduction, and transport activities.

The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.