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Finding the Number

Raphael Kopan and his colleagues at Washington University in St. Louis write in Cold Spring Harbor Protocols about a pyrosequencing-based method to determine the copy number of any allele from any genome. Their approach, called reference query pyrosequencing, takes "advantage of the fact that pyrosequencing can accurately measure the molar ratio of DNA fragments in a mixture that differ by a single nucleotide," they write. At Bench Marks, the Executive Editor of CSH Protocols David Crotty adds that "RQPS is rapid, inexpensive, sensitive, and adaptable to high-throughput approaches."

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.