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A team led by investigators at the University of Georgia presents in G3: Genes Genomes Genetics a 10,080-locus genetic map of the sunflower genome, which it produced based on multiple crosses. Integrating genotypic data for four sunflower mapping populations, the researchers produced a consensus linkage map of the sunflower genome, through which they found localized variation in recombination rates in several genomic regions and "observed several gaps up to 26 cM in length that completely lacked mappable markers in individual crosses," they report. However, because the regions varied by cross, the consensus map did not contain gaps, "clearly illustrating the value of simultaneously analyzing multiple mapping populations," the team adds.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.