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Figuring Out How to See the Glycome

In PNAS, Berkeley researchers discuss how to image the glycome. Usually, glycans are identified by using antibodies or lectins bound to probes. Since those methods are not easily applied to in vivo imaging, researchers are beginning to turn to metabolic labeling and fluorescent probes, say Scott Laughlin and Carolyn Bertozzi. "A collection of such reagents would enable a more thorough analysis of how glycan patterns change during normal and pathological processes," they write.

PNAS also notes that beginning with papers submitted this month, its authors will keep the copyright to their papers and the National Academies of Science will have the exclusive right to publish it.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.