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Figuring Out How to See the Glycome

In PNAS, Berkeley researchers discuss how to image the glycome. Usually, glycans are identified by using antibodies or lectins bound to probes. Since those methods are not easily applied to in vivo imaging, researchers are beginning to turn to metabolic labeling and fluorescent probes, say Scott Laughlin and Carolyn Bertozzi. "A collection of such reagents would enable a more thorough analysis of how glycan patterns change during normal and pathological processes," they write.

PNAS also notes that beginning with papers submitted this month, its authors will keep the copyright to their papers and the National Academies of Science will have the exclusive right to publish it.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.