Feel Good or Do Good?

Researchers at the University of North Carolina at Chapel Hill and elsewhere turned to the human genome to search for the molecular mechanisms that link psychological well-being to its attendant health advantages. As they describe in the Proceedings of the National Academy of Sciences this week, they examined the leukocyte basal gene expression profiles of 80 healthy people whose hedonic and eudaimonic well-being were also assessed.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.