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FDA Recommends Genotyping (But Not for Finding Your Soul Mate)

Over at PatentDocs, Kevin Noonan writes about a genotyping advisory that was included in a black box warning from FDA for abacavir, a GlaxoSmithKline drug used in HIV and AIDS treatment. Research has shown that patients with the HLA-B*5701 variant are significantly more likely to have a potentially life-threatening allergic reaction to the drug. Here's an excerpt from the FDA's advisory: "All patients should be screened for the HLA-B*5701 allele before starting or restarting treatment with abacavir or abacavir-containing medications."

 

The Scan

Vaccine Update Recommended

A US Food and Drug Administration panel recommends booster vaccines be updated to target Omicron, CNBC reports.

US to Make More Vaccines for Monkeypox Available

The US is to make nearly 300,000 vaccine doses available in the coming weeks to stem the spread of human monkeypox virus, according to NPR.

Sentence Appealed

The Associated Press reports that Swedish prosecutors are appealing the sentence given to a surgeon once lauded for transplanting synthetic tracheas but then convicted of causing bodily harm.

Genome Biology Papers on COVID-19 Effector Genes, Virtual ChIP-seq, scDART

In Genome Biology this week: proposed COVID-19 effector genes, method to predict transcription factor binding patterns, and more.