The US Food and Drug Administration wants to find out if the practice of modifying oocytes for use in in vitro fertilization is safe and scientifically sound, and held a hearing this week to launch a review of the process. Although it is sometimes referred to as three-parent baby-making, the procedure is not as kinky as it sounds, nor is it a likely set-up for a situation comedy, as very little DNA is contributed by the donor, but it has triggered some scientific, safety, and ethical concerns.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.