Nobel laureate and one of the founding fathers of modern cell biology, George Palade, has died at 95. He was one of the first to use electron microscopy, which helped him discover the ribosome and the action of secretory proteins. Palade shared the Nobel Prize in Physiology or Medicine in 1974 with Albert Claude and Christian de Duve.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.