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Farewell to Francis, and Scientists Break Down Personalized Medicine

Charlie Rose has a series of interviews, one with Navigenics' David Agus, Dean Ornish, and George Church, and another with Francis Collins. In the first, they talk about personalized medicine, personal genomics, and what people should understand and be aware of. "Initially, people should keep their expectations low," says Church, but Agus, who went on Lipitor as a prophylactic against his 80 percent increased risk of having a heart attack, thinks that "this is a very important way of understanding the genetics of disease." In another interview, Rose chats with Francis Collins about what's next for him -- he officially leaves his post at NHGRI today -- and for genetic research.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.