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A Fantasy Genome League?

Fantasy football and baseball leagues have caught on, but what about fantasy genome sequencing? At the New York Times, Olivia Judson says it's a good game for a rainy day. If she could sequence any organism, she'd go with the African coelacanth. She says this type of fish is interesting because its closest relative are lungfish and tetrapods and because it is a living fossil. "Preliminary genetic evidence suggests that coelacanths are, indeed, evolving more slowly than the rest of us. A study of their genome might help us to understand why," Judson writes.

What would you sequence?

The Scan

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.

Study Reveals Potential Sex-Specific Role for Noncoding RNA in Depression

A long, noncoding RNA called FEDORA appears to be a sex-specific regulator of major depressive disorder, affecting more women, researchers report in Science Advances.

New mRNA Vaccines Offer Hope for Fighting Malaria

A George Washington University-led team has developed mRNA vaccines for malaria that appear to provide protection in mice, as they report in NPJ Vaccines.

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.