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Expressing Sensitivity

Sep 23, 2008

Researchers at MIT found variations in gene expression that can inform clinicians about patients' response to chemotherapy. They tested how well 24 bone marrow cell lines from unrelated, healthy people grew when the cells were dosed with a chemotherapy drug. The researchers also used microarrays looked at the expression of 20,000 genes in those lines and used expression patterns to create a detection algorithm for genes associated with drug sensitivity. "This is incredibly encouraging for a clinical application," senior author Leona Samson tells Tech Review.

 

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