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Expressing Sensitivity

Researchers at MIT found variations in gene expression that can inform clinicians about patients' response to chemotherapy. They tested how well 24 bone marrow cell lines from unrelated, healthy people grew when the cells were dosed with a chemotherapy drug. The researchers also used microarrays looked at the expression of 20,000 genes in those lines and used expression patterns to create a detection algorithm for genes associated with drug sensitivity. "This is incredibly encouraging for a clinical application," senior author Leona Samson tells Tech Review.

 

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.