Exercise can lead to changes in people's overall health and risk of disease, the New York Times Well blog writes, but the mechanism through which those changes arise are not quite clear. "Several striking new studies, however, provide some clarity by showing that exercise seems able to drastically alter how genes operate," Gretchen Reynolds says in the Times.

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This Week in PLOS

Up All Night

This Week in PLOS

In Nature this week: method to detect single-nucleotide and copy-number alterations in single cells from archival tissue, and more.

China has announced new rules governing the use of stem cell treatments, Nature News reports.

Wired's Sarah Zhang expresses frustration as a microbiome study of homes uncovers expected bacteria.

A database containing genome sequences from strains of foodborne pathogens may enable regulators and companies to quickly identify outbreak sources, Reuters reports.