Exercise can lead to changes in people's overall health and risk of disease, the New York Times Well blog writes, but the mechanism through which those changes arise are not quite clear. "Several striking new studies, however, provide some clarity by showing that exercise seems able to drastically alter how genes operate," Gretchen Reynolds says in the Times.

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This Week in PLOS

Be Gone

This Week in PLOS

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Harold Varmus, the director of the National Cancer Institute, has announced that he is stepping down after nearly five years.