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Even Genes Believe in Networking

At Jackson Laboratory off the coast of Maine, geneticists have inbred a population of 5,000 mice to 40 strains, a process that has created rodents with identical genes. The mice, writes Carl Zimmer in an article in Discover magazine, are ideal for studying cancer, heart disease, and other ailments that are caused by networks of genes acting together, rather than traced to one single gene.

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.