Everyone know that smoking causes an increased risk of cancer, but researchers have also found direct evidence that smoking causes epigenetic changes in genes that block tumors, says The New Scientist's Nic Fleming. Reversing the changes could lead researchers down a new road to treat cancer, he adds.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.