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'An Enormous Amount of Data'

The Children's Hospital of Philadelphia announced this week that it has partnered with BGI to conduct large-scale genome sequencing projects. As Daily Scan sister publication GenomeWeb Daily News reported, "The [email protected] partnership will focus on using BGI's next-generation sequencing capabilities and CHOP's biobank and clinical phenotyping resources to discover which genes are involved in rare and common pediatric diseases." CHOP recently posted a video on YouTube of Hakon Hakonarson, director of the Center for Applied Genomics at Children's Hospital, discussing the advantages of partnering with BGI. The hospital will acquire 20 new next-gen, high-throughput sequencers, each of which can generate 800 gigabytes of data in a single run, Hakonarson says. "We can sequence three to four whole genomes per sequencer. You can just imagine the amount of data we'll have when we have all these units going for a year. This is an enormous amount of data," he adds. With all of these machines, CHOP will be able to automate the sequencing process and generate data much more efficiently than before, which will streamline the process of searching for disease-causing mutations, Hakonarson says.

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