ENCODE Explosion

The Encyclopedia of DNA Elements, or ENCODE, project just published a glut of papers —30 publications in a variety of journals from more than 440 researchers — looking at the function of various regions of the human genome. The project's "aim is to catalogue the 'functional' DNA sequences that lurk there, learn when and in which cells they are active and trace their effects on how the genome is packaged, regulated and read," writes Brendan Maher at Nature.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.