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Nobel prize-winner Edwin Krebs died from progressive heart failure. He was 91. Krebs shared the 1992 Nobel prize in physiology or medicine with Edmond Fischer for their elucidation of the regulatory role of reversible protein phosphorylation. "It was an embarrassingly simple reaction that we found," Fischer told the New York Times.

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A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.