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Eighty-Seven Percent Right Isn't Too Bad

Steven Briggs reports in PNAS that about 13 percent of the Arabidopsis proteome is incomplete due to missing and incomplete gene models. He and his colleagues isolated Arabidopsis proteins, determined the amino acid sequences of 144,079 peptides by tandem mass spectrometry, and found that while 126,055 peptides resided in existing gene models, 18,024 were novel. The authors say that "much is to be gained by joining forces, and incorporating proteomic evidence upfront into the genomics pipelines."

 

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.