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Eighty-Seven Percent Right Isn't Too Bad

Jan 01, 2009

Steven Briggs reports in PNAS that about 13 percent of the Arabidopsis proteome is incomplete due to missing and incomplete gene models. He and his colleagues isolated Arabidopsis proteins, determined the amino acid sequences of 144,079 peptides by tandem mass spectrometry, and found that while 126,055 peptides resided in existing gene models, 18,024 were novel. The authors say that "much is to be gained by joining forces, and incorporating proteomic evidence upfront into the genomics pipelines."

 

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