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Drugs: Keep ‘Em Coming

New advances in therapeutics seem to be everywhere these days, and two new studies point to this encouraging progress.  One, a pilot study conducted by Duke University Medical Center, has found that in conjunction with another chemo drug, Avastin helps to shrink deadly brain tumors by cutting off their blood supply.  They found that together, the two drugs stopped tumor growth up to two times as long as other therapies.

In another study, a new drug candidate has been found to reduce the mental retardation associated with Down syndrome.  The researchers, whose results were published in yesterday’s Nature Neuroscience, used mice models that had two copies of chromosome 16.  For a crib notes version, ScienceBlogs blogger Shelley Batts wraps it up pretty well.


The Scan

Vaccine Update Recommended

A US Food and Drug Administration panel recommends booster vaccines be updated to target Omicron, CNBC reports.

US to Make More Vaccines for Monkeypox Available

The US is to make nearly 300,000 vaccine doses available in the coming weeks to stem the spread of human monkeypox virus, according to NPR.

Sentence Appealed

The Associated Press reports that Swedish prosecutors are appealing the sentence given to a surgeon once lauded for transplanting synthetic tracheas but then convicted of causing bodily harm.

Genome Biology Papers on COVID-19 Effector Genes, Virtual ChIP-seq, scDART

In Genome Biology this week: proposed COVID-19 effector genes, method to predict transcription factor binding patterns, and more.